The Dome of the Rock sits on the Temple Mount in Jerusalem.  It is also called the Mosque of Omar.  It is said to be the spot from which Mohammed left earth to go to heaven, and it is the second most sacred mosque in the Muslim world.  In recent time, Jewish Rabbis have determined that the location of Solomon's Temple in far enough away from the Mosque so that they can build the new Temple without pulling the Mosque down.

I fully expect that, during the rule of "The Prince who shall come," the Antichrist, there will be the present Mosque, a new Jewish Temple, and a Christian cathedral for the Beast, Pope, or whoever rules.  He WILL plant his feet on the Temple Mount.  Daniel 11:45 "And he (Antichrist) shall plant the tabernacles of his palace between the seas in the glorious holy mountain; yet he shall come to his end, and none shall help him."